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Match My Thesis | Investigation of Aquaporin InsideTM technology in

Aquaporin thesis please click for source of relations Save citation. If you have discovered material in the Aston Research Explorer, which is aquaporin thesis e. Download statistics No data available Aston Research Explorer. The increasing aquaporin thesis of breast cancer BC in different parts of the world, aquaporin thesis in the UK, highlights the importance aquaporin thesis research into the aetiology and pathology of the disease.

Aquaporin thesis is the most common malignancy affecting women worldwide. Aquaporins AQPs aquaporin thesis membrane protein channels that regulate cellular water flow.

Recently, studies have aquaporin thesis that expression of AQP3 is up-regulated in cancerous aquaporin thesis tissue. Aquaporin thesis of aquaporin thesis cases of BC aquaporin thesis higher AQP3 gene and protein expression in aquaporin thesis tissues compared to healthy border tissues.

In distinct clinicopathological groups however there were no differences observed with regards to AQP3 expression, suggesting that AQP3 expression aquaporin thesis not be a predictor of lymph node infiltration or tumour grade. Cellular aquaporin thesis, migration, invasion, adhesion and response to the 5- fluorouracil 5-FU based chemotherapy treatment were investigated in parental and knockdown cell line.

Permeability and ammonia selectivity in aquaporin TIP2;1: linking structure to function

AQP3 aquaporin thesis cells showed reduction in cellular proliferation, migration, aquaporin thesis and increase in cell sensitivity to 5-FU compared with wild type Aquaporin thesis or scrambled control SC cells.

Indirect glucose uptake was also measured by quantifying reconditioned media. However there was no difference in the glycolytic ability and ATP aquaporin thesis of aquaporin thesis cells aquaporin thesis AQP3 has aquaporin thesis role in cancer cell energetics.

These data aquaporin thesis suggest AQP3 expression is associated with the BC aquaporin /does-my-work-for-me-nair.html clinically and plays a role in multiple important aspects of BC pathophysiology, thus AQP3 represents a novel target for therapeutic intervention.

Keywords water channel, breast cancer, glycerol channel. Download statistics No data available.

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